Spyre Therapeutics (SYRE) Options Chain
NASDAQ: SYREHealth CareBiotechnology: Pharmaceutical PreparationsUSD
At close: Oct 9, 4:00 PM ET · Delayed 15 min
After hours: 85.69 0.00%
Expiration date
- Expiration
- Oct 16, 2026
- Days to expiration
- 7
- Share price
- $85.69
- Put/call ratio (OI)
- 2.02
- Put/call ratio (volume)
- 0.52
- Expected move
- ±$7.95
- Open interest (C / P)
- 294 / 593
SYRE options summary
The SYRE options chain for the October 16, 2026 expiration lists 12 call and 10 put contracts, with 7 days until expiration. Open interest stands at 294 calls and 593 puts, a put/call ratio of 2.02, which is more bearish, with puts outnumbering calls. At-the-money implied volatility near the $85.00 strike is 67.0%, which implies the market expects a move of about ±$7.95 (9.3%) in Spyre Therapeutics stock by expiration.
The most open interest sits at the $85.00 call (212 contracts) and the $85.00 put (225 contracts).
Summary generated from market data by MetaCap's automated system. Methodology
SYRE options chain · October 16, 2026
| Calls | Puts | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Last | Bid | Ask | Strike | Bid | Ask | Last | |||||
| — | — | — | 55.00 | 0.00 | 4.90 | 0.05 | |||||
| — | — | — | 65.00 | 0.00 | 4.90 | 0.55 | |||||
| — | — | — | 70.00 | 0.00 | 4.90 | 0.40 | |||||
| 6.78 | 8.50 | 13.20 | 75.00 | 0.00 | 3.00 | 1.60 | |||||
| 6.70 | 5.50 | 7.60 | 80.00 | 0.35 | 4.90 | 4.10 | |||||
| 3.10 | 3.00 | 4.00 | 85.00 | 1.65 | 4.90 | 5.03 | |||||
| 1.55 | 0.00 | 2.95 | 90.00 | 3.80 | 7.90 | 5.30 | |||||
| 2.66 | 0.00 | 5.00 | 95.00 | 7.80 | 12.00 | 6.90 | |||||
| 3.50 | 0.00 | 4.90 | 100.00 | 12.40 | 16.50 | 10.69 | |||||
| 0.60 | 0.00 | 4.90 | 105.00 | 17.60 | 21.40 | 14.00 | |||||
| 1.35 | 0.00 | 4.90 | 110.00 | — | — | — | |||||
| 0.95 | 0.00 | 4.90 | 115.00 | — | — | — | |||||
| 0.65 | 0.00 | 4.90 | 120.00 | — | — | — | |||||
| 2.60 | 0.00 | 4.90 | 130.00 | — | — | — | |||||
| 1.61 | 0.00 | 4.90 | 145.00 | — | — | — | |||||
In-the-money callsIn-the-money puts. IV = implied volatility, OI = open interest (contracts). Each contract covers 100 shares. Quotes delayed at least 15 minutes.
Frequently asked questions
What is the SYRE put/call ratio?
For the October 16, 2026 expiration, the SYRE put/call ratio based on open interest is 2.02 (593 puts vs 294 calls), and 0.52 based on today's volume. A ratio above 1 means more puts than calls.
What is SYRE's implied volatility?
At-the-money implied volatility for SYRE options expiring October 16, 2026 is about 67.0%, an annualized estimate of how much the market expects Spyre Therapeutics stock to move.
How many SYRE option expiration dates are there?
SYRE has 6 listed expiration dates, from Oct 16, 2026 to Dec 17, 2027.
What does "in the money" mean?
A call is in the money when the strike price is below the current share price; a put is in the money when the strike is above it. In-the-money contracts have intrinsic value and are shaded in the table.