Spyre Therapeutics (SYRE) Options Chain

NASDAQ: SYREHealth CareBiotechnology: Pharmaceutical PreparationsUSD

85.69+5.79 (+7.25%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

Expiration date

Expiration: Mar 19, 2027
Days to expiration: 159
Share price: $85.69
Put/call ratio (OI): 0.92
Put/call ratio (volume): 1.14
ATM implied volatility: 62.0%
Expected move: ±$35.06
Open interest (C / P): 74 / 68

SYRE options summary

The SYRE options chain for the March 19, 2027 expiration lists 16 call and 7 put contracts, with 159 days until expiration. Open interest stands at 74 calls and 68 puts, a put/call ratio of 0.92, which is fairly balanced between calls and puts. At-the-money implied volatility near the $85.00 strike is 62.0%, which implies the market expects a move of about ±$35.06 (40.9%) in Spyre Therapeutics stock by expiration.

The most open interest sits at the $90.00 call (30 contracts) and the $100.00 put (21 contracts).

Summary generated from market data by MetaCap's automated system. Methodology

SYRE options chain · March 19, 2027

SYRE calls and puts by strike price. Shaded cells are in the money.
Calls							Puts
OI	Vol	IV	Last	Bid	Ask	Strike	Bid	Ask	Last	IV	Vol	OI
1	2	81.7%	53.80	44.50	49.10	40.00	—	—	—	—	—	—
11	5	72.3%	44.15	35.50	39.90	50.00	—	—	—	—	—	—
1	2	231.5%	50.08	53.60	58.00	55.00	—	—	—	—	—	—
5	5	71.8%	32.00	28.00	32.20	60.00	1.55	5.60	4.45	65.7%	5	17
0	—	—	23.40	0.00	0.00	65.00	2.50	6.70	6.10	62.5%	10	12
2	1	190.0%	28.81	42.80	47.00	70.00	—	—	—	—	—	—
1	1	181.1%	34.00	39.60	44.00	75.00	6.10	10.40	7.70	61.3%	1	2
7	1	68.8%	18.75	16.00	19.90	80.00	—	—	—	—	—	—
4	4	69.4%	36.30	14.00	17.70	85.00	9.80	14.00	14.00	54.6%	—	14
SYRE $85.69
30	—	136.9%	27.98	26.70	30.50	90.00	14.50	17.90	18.20	60.5%	—	2
1	1	68.2%	19.00	10.00	13.80	95.00	—	—	—	—	—	—
5	—	150.9%	17.50	26.50	31.00	100.00	21.00	24.40	25.00	59.4%	16	21
2	2	67.3%	12.36	7.00	10.70	105.00	0.00	0.00	22.20	—	—	0
3	3	66.3%	11.30	4.50	8.40	115.00	—	—	—	—	—	—
0	1	12.5%	21.00	0.00	0.00	125.00	—	—	—	—	—	—
1	—	66.2%	4.60	0.50	4.90	145.00	—	—	—	—	—	—

In-the-money callsIn-the-money puts. IV = implied volatility, OI = open interest (contracts). Each contract covers 100 shares. Quotes delayed at least 15 minutes.

Frequently asked questions

What is the SYRE put/call ratio?

For the March 19, 2027 expiration, the SYRE put/call ratio based on open interest is 0.92 (68 puts vs 74 calls), and 1.14 based on today's volume. A ratio above 1 means more puts than calls.

What is SYRE's implied volatility?

At-the-money implied volatility for SYRE options expiring March 19, 2027 is about 62.0%, an annualized estimate of how much the market expects Spyre Therapeutics stock to move.

How many SYRE option expiration dates are there?

SYRE has 6 listed expiration dates, from Oct 16, 2026 to Dec 17, 2027.

What does "in the money" mean?

A call is in the money when the strike price is below the current share price; a put is in the money when the strike is above it. In-the-money contracts have intrinsic value and are shaded in the table.