MetaCap

Upstream Bio Insider Trades

NASDAQ: UPBHealth CareBiotechnology: Pharmaceutical PreparationsUSD

4.70+0.15 (+3.30%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

After hours: 4.70 0.00%

Last 12 months

Purchases
0 · $0
Sales
15 · $104.80K
Shares bought / sold
0 / 15.06K
Net activity
Net selling $104,796

Upstream Bio insider activity

Over the last 12 months, Upstream Bio insiders reported 20 transactions on SEC Form 4: 0 open-market purchases and 15 sales. Insiders bought $0 and sold $104,796 worth of stock, for net insider selling of $104,796. The largest seller was Sutherland Everett Rand, with $43,725 in reported sales.

The most recent filing shows GRAY MICHAEL (CFO and COO) selling 853 shares at $5.49 on Sep 16, 2026. Insider sales are common for compensation, tax and diversification reasons, while open-market purchases are rarer; tracking both helps put UPB's ownership changes in context.

Summary generated from market data by MetaCap's automated system. Methodology

UPB insider transactions

Upstream Bio insider transactions
DateInsiderTypeSharesValueFiling
Sep 16, 2026Houghton AdamChief Business OfficerSale700$3.84KForm 4
Sep 16, 2026Deykin AaronChief Medical OfficerSale895$4.91KForm 4
Sep 16, 2026Ambrose AllisonGeneral CounselSale485$2.66KForm 4
Sep 16, 2026Sutherland Everett RandChief Executive OfficerSale2,095$11.50KForm 4
Sep 16, 2026GRAY MICHAELCFO and COOSale853$4.68KForm 4
Jun 16, 2026Ambrose AllisonGeneral CounselSale477$2.91KForm 4
Jun 16, 2026Houghton AdamChief Business OfficerSale700$4.27KForm 4
Jun 16, 2026Sutherland Everett RandChief Executive OfficerSale2,095$12.78KForm 4
Jun 16, 2026Deykin AaronChief Medical OfficerSale895$5.46KForm 4
Jun 16, 2026GRAY MICHAELCFO and COOSale853$5.20KForm 4
Mar 16, 2026Sutherland Everett RandChief Executive OfficerSale2,093$19.44KForm 4
Mar 16, 2026Deykin AaronChief Medical OfficerSale894$8.31KForm 4
Mar 16, 2026GRAY MICHAELCFO and COOSale852$7.92KForm 4
Mar 16, 2026Houghton AdamChief Business OfficerSale699$6.49KForm 4
Mar 16, 2026Ambrose AllisonGeneral CounselSale475$4.41KForm 4
Jan 2, 2026Sutherland Everett RandChief Executive OfficerAward75,000—Form 4
Jan 2, 2026Houghton AdamChief Business OfficerAward25,000—Form 4
Jan 2, 2026Deykin AaronChief Medical OfficerAward32,000—Form 4
Jan 2, 2026GRAY MICHAELCFO and COOAward30,500—Form 4
Jan 2, 2026Ambrose AllisonGeneral CounselAward17,000—Form 4
Oct 15, 2024ORBIMED ADVISORS LLC & OrbiMed Capital GP VIII LLC & OrbiMed Advisors Israel II Ltd & OrbiMed Israel GP II, L.P.DirectorBuy660,000$11.22MForm 4
Oct 15, 2024ORBIMED ADVISORS LLC & OrbiMed Capital GP VIII LLC & OrbiMed Advisors Israel II Ltd & OrbiMed Israel GP II, L.P.DirectorConversion2,887,833—Form 4
Oct 15, 2024ORBIMED ADVISORS LLC & OrbiMed Capital GP VIII LLC & OrbiMed Advisors Israel II Ltd & OrbiMed Israel GP II, L.P.DirectorBuy165,000$2.81MForm 4
Oct 15, 2024ORBIMED ADVISORS LLC & OrbiMed Capital GP VIII LLC & OrbiMed Advisors Israel II Ltd & OrbiMed Israel GP II, L.P.DirectorConversion721,956—Form 4
Oct 15, 2024Chimovits ErezDirectorBuy660,000$11.22MForm 4
Oct 15, 2024Chimovits ErezDirectorConversion2,887,833—Form 4
Oct 15, 2024Chimovits ErezDirectorBuy165,000$2.81MForm 4
Oct 15, 2024Chimovits ErezDirectorConversion721,956—Form 4

Transaction codes follow SEC Form 4: P = open-market purchase, S = open-market sale, A = grant or award, M = option exercise, F = shares withheld for taxes. About Form 4

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