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Upstream Bio Inc. Company Profile

NASDAQ: UPBHealth CareBiotechnology: Pharmaceutical PreparationsUSD

4.55-0.06 (-1.30%)

At close: Oct 8, 4:00 PM ET · Delayed 15 min

Upstream Bio at a glance

Upstream Bio Inc. (NASDAQ: UPB) is a Biotechnology: Pharmaceutical Preparations company in the Health Care sector headquartered in Waltham, MA. Upstream Bio is led by Dr. E. Rand Sutherland M.D., M.P.H. and employs about 75 people. The company's shares have traded publicly since 2024.

At a market capitalization of $252.5 million, it is considered a small-cap company. Its SEC Central Index Key (CIK) is 0002022626, which identifies the company's filings on EDGAR.

Summary generated from market data by MetaCap's automated system. Methodology

What does Upstream Bio do?

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Business description based on the company's public filings.

Company information

Legal name
Upstream Bio Inc.
Ticker
NASDAQ: UPB
Industry
Biotechnology: Pharmaceutical Preparations
CEO
Dr. E. Rand Sutherland M.D., M.P.H.
Employees
75
Headquarters
890 Winter Street, Waltham, MA, United States
Phone
781 208 2466
IPO year
2024
Market cap
$252.49M
SEC CIK
0002022626
Latest annual report
10-K · Mar 26, 2026

Companies similar to Upstream Bio

UPB peer companies
CompanyPrice% ChgMarket capCompare
AMRNAmarin Corporation plc11.99-0.25%$253.26Mvs UPB
ACIUAC Immune SA2.55-0.78%$253.54Mvs UPB
VCREVicore Pharma Holding AB ADR8.82+1.85%$248.41Mvs UPB
ZNTLZentalis Pharmaceuticals Inc.2.51-1.57%$246.29Mvs UPB
VOGXVogenx Inc17.49+8.23%$259.82Mvs UPB
LFCRLifecore Biomedical Inc.6.43-0.16%$243.73Mvs UPB
IMRXImmuneering Corporation Class A3.74-3.11%$241.97Mvs UPB
QTTBQ32 Bio Inc.8.09+1.25%$240.83Mvs UPB

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